The director of the National Cancer Research Centre (CNIO), María Blasco, has released an open letter to the institution's Board of Trustees, where she defends her leadership and reveals plans to pursue legal action against various media outlets. She accuses them of orchestrating a campaign filled with misinformation aimed at undermining the reputation of both the CNIO and her personal integrity. In her correspondence, Blasco highlights the rapid spread of this alleged campaign through social media, characterized by insults, defamation, and even threats against her life. Blasco draws parallels between the current situation and historical instances of dehumanization, arguing that public figures, including scientists, can become targets of mass hatred. This letter comes just before an upcoming board meeting, where trustees will discuss the potential dismissal of the current leadership during one of the most challenging periods since the CNIO's establishment in 1998. In her letter, Blasco outlines her responses during the crisis, including holding an assembly with CNIO staff to provide transparency and seeking assistance from the Ombudsman. The Ombudsman, led by Ángel Gabilondo, declined to conduct an independent audit as requested by Blasco. She also notes that she has participated in interviews with various media outlets and has sought corrections from those that published misleading information. Blasco's communication asserts that the CNIO has requested the Secretary General of Research to authorize state legal representation to address defamation claims stemming from the misinformation campaign. She emphasizes the need for accountability from those responsible for promoting this narrative that threatens the reputation of Spanish scientific excellence. Additionally, Blasco appeals to the government for increased funding for the CNIO, stressing the importance of a budget that has not seen an increase since 2014. She advocates for a recognition system for long-serving researchers within the institution. The conclusion of her letter underscores the gravity of the situation, stating that the individuals behind the misinformation campaign are identifiable, and she urges the Board to make a significant decision regarding her management. Blasco expresses her desire to complete her work constructively, paving the way for her successor to build upon her achievements.